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In order to meet the required sample size, an additional 521 open-label patients were recruited and identically treated with vedolizumab.

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In another study, 5 kidney transplant recipients treated with cyclosporine, azathioprine, and prednisolone were given single 20 mg doses of simvastatin and compared with 5 patients treated with azathioprine and prednisolone (without cyclosporine).

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This ointment contains Cyclosporine, an FDA-approved anti-inflammatory immunosuppressive drug that reduces swelling and irritation.

It also affects the Skin, Joints, Eyes, Liver, Kidneys and the Pancreas.

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If you are taking cyclosporine (modified) to treat rheumatoid arthritis, it may take 4 to 8 weeks for your symptoms to improve.

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Although concomitant administration of diclofenac does not affect blood concentrations of Cyclosporine, it has been associated with approximate doubling of diclofenac blood concentrations and occasional reports of reversible decreases in renal function.

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Caspofungin, an echinocandin antifungal, appears to induce tacrolimus, resulting in an average 20% decrease in immunosuppressive effect.

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Do not use cyclosporine ophthalmic if you have any type of infection in the eye(s).

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When this happens, necrosis (death of tissue) and gangrene may set in, sometimes making it necessary to have the affected part(s) amputated.

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WASHINGTON -- Perinatal outcomes were slightly, but not significantly, better in renal transplant recipients who were, immunosuppressed with cyclosporine, compared with those given azathioprine, according to findings from a study involving 59 pregnant women at a single research center.

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Food and Drug Administration (FDA) is requiring the makers of certain immunosuppressant drugs to update their labeling to reflect that immunosuppressed patients are at increased risk for opportunistic infections, such as activation of latent viral infections, including BK virus-associated nephropathy.

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Because of the danger of oversuppression of the immune system, which can also increase susceptibility to infection, cyclosporine should not be administered with other immunosuppressive agents except adrenal corticosteroids.

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