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My gall bladder was acting up and the pain was terrible. I took a Protonix as soon as I got out of the doctors office (with a sandwich and doctor pepper) about 15 seconds later I was burping like CRAZY. Viola!! The pain subsided considerably in less than 3 minutes. AN hour later it was like I never even had the pain! I felt MUCH, MUCH better.
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Esophageal ulcer: Had problems off and on with horrible heartburn throughout my teens years until I ended up with an ulcer due to undiagnosed acid reflux and other problems. Was prescribed Protonix and it was the only thing that worked. Since then I have been able to use Tagamet (cimetidine) for every day use, along with watching what I eat, but the Protonix is awesome.
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Data comparing the 2 types of agents for preventing gastrointestinal bleeding in critically ill patients are limited.
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Regular exercises and a walk after your meals help in settling the food down and reduce reflux.
Pantoprazole is used to treat the symptoms of GERD, allow the esophagus to heal, and prevent further damage to the esophagus.
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Pantoprazole works by controlling and curing acid issues that may arise in the stomach.
ACIPHEX is indicated for short-term (4 to 8 weeks) treatment in the healing and symptomatic relief of erosive or ulcerative gastroesophageal reflux disease (GERD).
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Clopidogrel needs metabolic activation predominantly by the hepatic cytochrome P450 isoenzyme Cytochrome 2C19 (CYP2C19) and proton pump inhibitors (PPIs) are extensively metabolized by the CYP2C19 isoenzyme as well.
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In subgroup analyses, patients who had a bloody NG aspirate pre-endoscopy (but not those with clear or coffee-grounds aspirates) had significantly fewer units of blood transfused and hospital days (28).
The medication is proven effective for conditions such as the esophageal damage caused by acid reflux, which occurs in GERD, or for peptic ulcers that occur as a result of the overproduction of gastric acid in Zollinger-Ellison syndrome.
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Postmarketing ExperienceThe following adverse reactions have been identified during postapproval use of pantoprazole sodium delayed-release tablets.
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Not only did it take my heartburn away after 2 days of use, it took it away for the remainder of the time I used it.
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If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
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In a clinical pharmacology study, PROTONIX 40 mg given once daily for 2 weeks had no effect on the levels of the following hormones: cortisol, testosterone, triiodothyronine (T 3), thyroxine (T 4), thyroid-stimulating hormone (TSH), thyronine-binding protein, parathyroid hormone, insulin, glucagon, renin, aldosterone, follicle-stimulating hormone, luteinizing hormone, prolactin, and growth hormone.
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Associations between different forms of gastro-esophageal reflux disease.
Pantoprazole sodium delayed-release tablets are contraindicated in patients with known hypersensitivity to any component of the formulation or any substituted benzimidazole.
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Lastly, although esomeprazole treatment in GERD has been reported to result in improvement of health-related quality of life (QoL) indices, no clinical trials have evaluated the possible differential effects of different PPIs on QoL in GERD.
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Despite the availability of medical, surgical, and endoscopic options, optimal management strategies remain unsettled.
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Pantoprazole suspension should only be administered in apple juice or applesauce, not in water or other liquids, or foods.
In the absence of Helicobacter pylori infection, the long-term use of PPIs has not been convincingly proven to cause or be associated with the progression of pre-existing chronic gastritis or gastric atrophy or intestinal metaplasia.
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German researchers found that people 75 or older who regularly take the heartburn medications had a 44 percent increased risk of dementia, compared with seniors not using the drugs.
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Gastro-esophageal reflux disease in the elderly.
In 2 controlled trials where daily doses up to 40 mg were given for up to 8 weeks, there were no dose-related adverse side effects associated with the use of this drug.
There were no discontinuations because of AEs, no serious AEs, and no statistically significant differences between the dose groups in the occurrence of any specific AEs in either study.
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Ben Wedro practices emergency medicine at Gundersen Clinic, a regional trauma center in La Crosse, Wisconsin.
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To take AcipHex Sprinkle, open the capsule and sprinkle the medicine into a spoonful of soft food such as applesauce, yogurt, or baby food made from fruit or vegetable.
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Use healthy oils, such as olive oil or vegetable oil.
This effect is dose- related and leads to inhibition of both basal and stimulated gastric acid secretion irrespective of the stimulus.
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Pantoprazole sodium for injection should be discontinued as soon as patient is able to resume treatment with oral pantoprazole tablets.
Both the reconstituted solution and the admixed solution do not need to be protected from light.
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Metabolism: Pantoprazole is extensively metabolized in the liver through the cytochrome P450 (CYP) system.
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GERD: 15-30mg orally once daily before meal.
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The expiry date of medications intended for IV administration following reconstitution or dilution is often limited to about 24 h, even when data on extended stability exist, because of the potential for breaks in sterility and contamination of the product.
In fact, symptoms and esophagitis recur quickly if therapy is not continuative and long-term treatment appears to be the key to effective management.
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Another endpoint will be the 24-hour esophageal reflux time after a single dose of study medication.
Potential safety issue for health-care professionals attempting to connect these system components manually or with mechanical assistance.
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